Table 2 Repair of DNA damage in five bladder cancer cell lines following exposure to X-irradiation

From: Potential use of the alkaline comet assay as a predictor of bladder tumour response to radiation

Cell Line

SF2 a

Residual damage (30 min) b

Residual damage (60 min) b

T 1/2 c (min)

T24

0.70±0.01

4.38±0.25

2.31±0.37

8.8

UM-UC-3

0.59±0.03

1.06±0.07

0.34±0.02

5

TCC-SUP

0.62±0.02

0.84±0.01

0.18±0.02

4

RT112

0.67±0.01

0.50±0.03

0.00±0.002

3.0

HT1376

0.77±0.07

0.00±0.002

0.00±0.002

2.5

  1. aSurviving fraction of cells exposured to 2 Gy, determined by performing three independent experiments each containing three replicates.
  2. bResidual DNA damage calculated by subtracting the control tail moment from that remaining at 30 and 60 min in Figure 5.
  3. cTime (min) for half of the initial damage to be repaired.
  4. The data represent the mean±s.e. of three independent experiments.
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