Table 4 Haematologic toxicity: maximum toxicity grade in any course

From: Randomised phase II study of docetaxel/cisplatin vs docetaxel/irinotecan in advanced non-small-cell lung cancer: a West Japan Thoracic Oncology Group Study (WJTOG9803)

 

Docetaxel/cisplatin (% pts)

Docetaxel/irinotecan (% pts)

Toxicity/grade

2

3

4

2

3

4

Leucopenia*

31

43

4

26

40

16

Neutropenia*

10

31

43

4

23

61

Anaemia

47

10

2

46

7

0

Thrombocytopenia**

10

4

0

0

0

0

Febrile neutropenia

 

20

  

28

 
  1. pts=patients.
  2. *P<0.01 for grade 4;
  3. **P<0.01 for the sum of grades 2 and 3.