Table 2 Radiation sensitivity parameters n, D0 and δS for irradiated cells obtained from fitting of the MTT assay data of cells from patients GBM1, GBM2, GBM3, GCG (malignant karyotyped) and N1 (normal karyotyped)
From: Radiation sterilisation of cultured human brain tumour cells for clinical immune tumour therapy
Uncertainty factor | δS=0 | δS≠0 | |||
---|---|---|---|---|---|
Fitting parameters | n | D0 (Gy) | δS | n | D0 (Gy) |
Cell lines | |||||
GBM1 | 0.92±0.07 | 171±45 | 0.59±0.023 | 0.41±0.04 | 9.6±5.0 |
GBM2 | 0.98±0.08 | 22.8±5.9 | 0.14±0.04 | 0.86±0.06 | 11.6±3.2 |
GBM3 | 0.99±0.052 | 26.9±3.6 | 0.17±0.04 | 0.83±0.05 | 13.2±4.1 |
Average GBM1–3 | 0.86±0.16 | 30.0±8.1 | 0.14±0.03 | 0.85±0.10 | 12.4±3.2 |
GCG | 1.00±0.04 | 13.0±3.4 | 0.10±0.02 | 0.91±0.03 | 7.1±2.2 |
N1(Normal) | 0.99±0.03 | 166±14 | 0.24±0.31 | 0.75±0.30 | 108±75 |