Table 1 Proliferation of PANC-1 cells expressing EGFP or EGFP–MTA1

From: Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells

Cell clone

Doubling time (h) (±s.e.m, n=3)

Increase in doubling time (%) compared to EGFP-21 cells

EGFP-21

37.4±1.7

MTA1-7

43.6±1.4

16% (P< 0.01, t-test)

MTA1-8

52.9±0.9

40% (P< 0.001, t-test)

MTA1-9

56.0±2.7

50% (P< 0.001, t-test)

MTA1-16

48.4±1.4

28% (P< 0.001, t-test)

  1. PANC-1 cells expressing either EGFP (EGFP-21) or EGFP–MTA1 (MTA1-7, MTA1-8, MTA1-9, MTA1-16) were grown in DMEM supplemented with 10% FCS. Cell growth was determined by counting the cells every 48 h over a period of 12 days. Growth curves were calculated by nonlinear regression analysis for exponential growth and the average doubling times were determined using the GraphPad Prism 3.02 software. The means ±s.e.m of three independent experiments are presented. Statistical analysis was performed using the Student's t-test.