Table 1 Area under the plasma or tissue concentration time curve (AUC) for resveratrol and DMU 212 in mice that received these agents (240mg/kg) i.g

From: Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4′-tetramethoxystilbene

 

AUC (nmoles ml−1 or g−1 min)

 

Tissue

Resveratrol

DMU 212

AUCres/AUCDMU

Plasma

863

246

3.5

Liver

2150

432

5

Kidney

785

566

1.5

Lung

1123

778

1.5

Heart

2072

750

3

Brain

103

193

0.5

Intestinal mucosa

36 690

369 315

0.1

Colonic mucosa

2869

19 256

0.15

  1. AUC values were calculated from the curves shown in Figure 2 using the mean plasma or tissue concentration values between 0 and 120 min postadministration.
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