Table 2 Features of daughter ion spectra obtained by tandem mass spectrometry of molecular ions (M+H)+ of DMU 212 and four metabolites isolated from peaks in high-performance liquid chromatograms of extracts of livers of micethat had received DMU 212 (240 mg kg−1) and of peaks of authentic reference compounds

From: Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4′-tetramethoxystilbene

 

Authentic standard m/z

Liver extract m/z

DMU 212

301 (M+H)+ (55)

301 (M+H)+ (80)

 

270 (100)

270 (100)

 

286 (35)

286 (50)

4,4′-Di-desmethyl-DMU 212

273 (M+H)+ (23)

273 (M+H)+ (25)

 

198 (100)

198 (50)

 

181 (62)

181 (81)

3-Desmethyl-DMU 212

287 (M+H)+ (10)

287 (M+H)+ (75)

 

227 (72)

227 (20)

 

195 (70)

195 (18)

4′-Desmethyl-DMU 212

287 (M+H)+ (10)

287 (M+H)+ (60)

 

256 (100)

256 (100)

 

272 (80)

272 (47)

3′-Hydroxy-DMU 212

317 (M+H)+ (31)

317 (M+H)+ (21)

 

225 (55)

225 (100)

 

286 (22)

286 (10)

  1. Only three prominent product ions are shown. Relative abundance in percentage is shown in parentheses.
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