Table 1 Prognostic factor analysis of 2192 women with breast cancer, ORCC, 1994–1997

From: Survival of women with breast cancer in Ottawa, Canada: variation with age, stage, histology, grade and treatment

 

Univariate analysis

Multivariate analysisa

 

Univariate analysis

Multivariate analysisa

Variables

RER (95% CI)

P-valueb

RER (95% CI)

P-valueb

Variables

RER (95% CI)

P-valueb

RER (95% CI)

P-valueb

Stage

 

0.00000

 

0.00000

Age (years)

 

0.00005

 

0.00004

 Stage I

1.00

 

1.00

 

 0–39

1.00

 

1.00

 

 Stage II

4.54 (2.32,8.89)

 

3.05 (1.55,5.99)

 

 40–49

0.45 (0.29,0.68)

 

0.46 (0.30,0.71)

 

 Stage III

15.64 (7.78,31.44)

 

8.28 (4.08,16.83)

 

 50–69

0.29 (0.19,0.44)

 

0.45 (0.31,0.69)

 

 Stage IV

52.35 (26.74,82.47)

 

25.80 (12.88,51.65)

 

 70+

0.47 (0.29,0.75)

 

0.85 (0.55,1.31)

 

Treatment

 

0.00000

 

0.00592

Histology

 

0.00257

 

0.08866

 Chemotherapy

1.00

 

1.00

 

 Ductal carcinoma

1.00

 

1.00

 

 Radiotherapy

0.15 (0.06,0.40)

 

0.97 (0.42,2.23)

 

 Lobular carcinoma

0.50 (0.24,1.01)

 

0.66 (0.37,1.16)

 

 Surgery

0.12 (0.06,0.25)

 

0.47 (0.24,0.94)

 

 Others

1.76 (1.16,2.66)

 

1.18 (0.80,1.74)

 

 C+Rc

0.74 (0.44,1.27)

 

1.07 (0.63,1.81)

 

Grade

 

0.00000

 

0.00007

 S+Cc

0.25 (0.18,0.36)

 

0.58 (0.39,0.86)

 

 Grade 1

1.00

 

1.00

 

 S+Rc

0.02 (0.01,0.12)

 

0.35 (0.15,0.81)

 

 Grade 2

7.26 (1.77,29.72)

 

2.68 (1.00,7.15)

 

 S+C+Rc

0.19 (0.11,0.30)

 

0.53 (0.33,0.85)

 

 Grade 3

18.37 (4.55,74.16)

 

4.87 (1.84,12.87)

 
  1. Relative survival rate (RER) estimated according to regression models based on relative survival.
  2. aAdjusted for all the other variables in the table.
  3. bP-value from likelihood ratio test.
  4. cC=chemotherapy; R=radiotherapy; S=surgery.
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