Table 1 c-myc gene copy amplification analysis by FISH in poor prognosis human breast tumour samples

From: Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses

Amplification index (#c-myc signals/# control signals)+

Percentage of samples with FISH ratios in each category

1.0–1.7

30%

14 out of 46

1.8–1.99

20%

Nine out of 46

2.0–2.9

39%

18 out of 46

>3.0

11%

Five out of 46

  1. Analysis was conducted on 46 individual paraffin-embedded tissue samples with negative progesterone receptor status, positive lymph node involvement and high tumour grade. +Normal control ratio is 1.
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