Table 2 Feeding response of healthy subjects and weight-losing cancer patients
Healthy subjects (n=6) | Cancer patients (n=7) | ||
---|---|---|---|
Median (range) | Median (range) | P-value | |
Area under the curve over the feeding period (200 min) | |||
Insulin (IU l−1) | 4.57 (2.82–9.05) | 3.73 (2.72–7.26) | 0.366 |
Glucose (mol l−1) | 1.09 (0.94–1.20) | 1.44 (1.15–1.76) | 0.005 |
Cortisol (mmol l−1) | 58.8 (52.8–81.3) | 81.9 (65.3–128) | 0.022 |
Leptin (mg l−1) | 2.59 (0.94–9.97) | 0.33 (0.22–2.69) | 0.022 |
Interleukin-6 (ng l−1) | <2 (<2–<2) | 753 (420–1554) | 0.048 |
Energy expenditure (cal) | 341.8 (285.8–435.3) | 289.8 (212.4–355.0) | 0.138 |
Energy expenditure (cal (kg body weight)−1) | 4.61 (3.56–5.33) | 5.14 (4.16–5.63) | 0.101 |
Fat oxidation (g) | 10.9 (8.1–12.5) | 9.4 (2.4–18.1) | 1.000 |
Fat oxidation (mg (kg body fat mass)−1) | 380 (286–619) | 678 (142–1036) | 0.101 |