Table 1 Relationships between LOH of FHIT and microsatellite makers and clinicopathologic parameters of patient analysed
LOH | ||||
|---|---|---|---|---|
Makers | Clinicopathologic parameters | No.of cases with LOH(%) | No.of cases without LOH (%) | P-value |
D3S1766 | Squamous cell carcinoma | 10 (90.9) | 1 (9.1) | 0.049 |
Adenocarcinoma | 9 (52.9) | 8 (47.1) | ||
D3S1766 | p53 (+)a | 9 (100) | 0 (0) | 0.026 |
p53 (−)a | 10 (52.6) | 9 (47.4) | ||
D3S1766 | Fhit(+)a | 6 (54.5) | 5 (45.5) | 0.409 |
Fhit(−)a | 13 (76.5) | 4 (23.5) | ||
D3S1289 | Male in adenocarcinoma | 6 (75) | 2 (25) | 0.028 |
Female in adenocarcinoma | 4 (23.5) | 13 (76.5) | ||
LOH loci ⩾1 | Smoker | 20 (83.3) | 4 (16.7) | 0.439 |
Nonsmoker | 30 (90.9) | 3 (9.1) | ||
