Table 1 Patient demographics

From: Pegylated liposomal doxorubicin in combination with mitomycin C, infusional 5-fluorouracil and sodium folinic acid. A phase-I-study in patients with upper gastrointestinal cancer

Variable

No. of patients (%)

Enrolled

27 (100)

Assessable

25 (93)

Median age

63 (range, 38–74)

Gender

 Male

16 (59)

 Female

11 (41)

Performance status (ECOG)

 Median

1

 0

1 (4)

 1

17 (63)

 2

9 (33)

Tumor origin

 

 Pancreatic cancer

12 (44)

 Gastric cancer

11 (41)

 Cholangiocarcinoma

3 (11)

 Cancer of unknown primary (adenocarcinoma)

1 (4)

Prior chemotherapy

 None (gastric cancer)

10 (37)

 One line

13 (48)

 Two lines

4 (15)

Gemcitabine

15 (56)

5-fluorouracil-based (i.v. or oral)

8 (30)

Others (irinotecan, oxaliplatin)

2 (7)

Tumor localisation

 Primary

19 (70)

 Liver

17 (63)

 Lymph nodes

6 (22)

 Peritoneal carcinomatosis

10 (37)

 Other

2 (7)

  1. i.v.=intravenous.