Table 1 Selected characteristics of colorectal cancer cases and controls, the Singapore Chinese Health Study

From: Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: The Singapore Chinese Health Study

Characteristics

Controls (n=1177)

Cases (n=310)

P-valuea

 Mean age±s.d.b (years)

56.5±8.1

61.3±7.5

<0.001

 

Number (%)

 

Sex

   

 Males

509 (43.2)

178 (57.4)

<0.001

 Females

668 (56.8)

132 (42.6)

 

Dialect group

   

 Cantonese

571 (48.5)

138 (44.5)

0.23

 Hokkien

606 (51.5)

172 (55.5)

 

Level of education

   

 No formal schooling

318 (27.0)

95 (30.6)

0.01

 Primary school

504 (42.8)

151 (48.7)

 

 Secondary school

288 (24.5)

54 (17.4)

 

 A level/university

67 (5.7)

10 (3.2)

 

Body mass index (kgm2)

   

20

187 (15.9)

46 (14.8)

0.04

 20−<24

659 (56.0)

151 (48.7)

 

 24−<28

267 (22.7)

92 (29.7)

 

 28+

64 (5.4)

21 (6.8)

 

Cigarette smoking

   

 Never smokers

853 (72.5)

184 (59.4)

<0.001

 Former smokers

131 (11.1)

52 (16.8)

 

 Current smokers

193 (16.4)

74 (23.9)

 

Frequency of alcohol consumption

   

 Nondrinkers

964 (81.9)

243 (78.4)

0.14

 Monthly

85 (7.2)

21 (6.8)

 

 Weekly

93 (7.9)

29 (9.4)

 

 Daily

35 (3.0)

17 (5.5)

 

Familial history of colorectal cancer

   

 No

1149 (97.6)

297 (95.8)

0.12

 Yesc

28 (2.4)

13 (4.2)

 

Median (5th percentile, 95th percentile)

Total calories (kcal day−1)

1483.5 (829.9, 2477.5)

1494.0 (819.3, 2589.2)

0.54

Total fat (g day−1)

40.5 (19.6, 81.7)

39.8 (19.0, 77.1)

0.66

SFAs (g day−1)

14.0 (5.9, 30.0)

13.7 (5.8, 29.2)

0.62

MUFAs (g day−1)

13.6 (6.3, 28.0)

13.4 (6.1, 26.5)

0.88

PUFAs (g day−1)

8.1 (3.3, 18.6)

7.9 (3.4, 16.5)

0.74

N-3 PUFAs (g day−1)

0.8 (0.4, 1.7)

0.8 (0.4, 1.7)

0.94

N-6 PUFAs (g day−1)

7.2 (2.9, 16.8)

7.0 (3.0, 14.9)

0.75

Fiber (g day−1)

12.2 (5.0, 23.1)

11.9 (4.3, 22.5)

0.83

Calcium (mg day−1)

373.5 (156.7, 853.5)

363.4 (158.8, 773.6)

0.56

Folate (μg day−1)

146.0 (64.1, 277.7)

147.1 (57.9, 286.9)

0.65

  1. aTwo-sided P-values derived from t-test (for age), χ2 test (for categorical variables) or Wilcoxon rank sum test (for nutrient intakes).
  2. bMean age at recruitment into the cohort, s.d.=standard deviation.
  3. cAny of first-degree relatives had colorectal cancer.