Table 2 COX-2 −765G>C genotype and dietary intake of n-6 PUFAs in relation to risk of colorectal cancer, the Singapore Chinese Health Study

From: Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: The Singapore Chinese Health Study

  

Colorectal cancer

Colon cancer

Rectal cancer

 

Controls

Cases

OR (95% CI)a

Cases

OR (95% CI)a

Cases

OR (95% CI)a

COX-2 genotype

       

 GG

1067

273

1.00

155

1.00

118

1.00

 GC/CC

110

37

1.18 (0.77–1.79)

25

1.50 (0.92–2.47)

12

0.87 (0.45–1.66)

Dietary n-6 PUFAs in quartile b

       

 1st (low)

260

70

1.00

42

1.00

28

1.00

 2nd

297

83

1.08 (0.72–1.60)

48

1.15 (0.70–1.87)

35

0.97 (0.55–1.71)

 3rd

312

72

1.00 (0.65–1.53)

45

1.09 (0.64–1.83)

27

0.82 (0.44–1.54)

 4th (high)

308

85

1.04 (0.63–1.70)

45

1.04 (0.56–1.92)

40

0.99 (0.49–1.99)

  1. aORs were adjusted for age at recruitment, year of recruitment, gender, dialect group, level of education, body mass index, smoking status, frequency of alcohol consumption, and familial history of colorectal cancer; CI=confidence interval.
  2. bIn addition to all variables listed above, OR were adjusted for total energy intake.
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