Figure 4 | British Journal of Cancer

Figure 4

From: Isolation and characterisation of a human anti-idiotypic scFv used as a surrogate tumour antigen to elicit an anti-HER-2/neu humoral response in mice

Figure 4

BIACORE experiments: (A) binding kinetics of anti-Id scFv 40, 69 and irrelevant scFv on trastuzumab F(abi′)2 fragments immobilised on a CM5 sensor chip and equilibrium affinity constants (inserted Table), (B) inhibition of HER-2/neu ECD-Fc fusion protein binding on trastuzumab F(ab′)2 fragments immobilised on a CM5 sensorchip by anti-Id scFv 69.

Back to article page