Table 1 Predicted amino-acid sequences of the CDR3 regions of VH and VL domains of the three unique scFv 39, 40 and 69a

From: Isolation and characterisation of a human anti-idiotypic scFv used as a surrogate tumour antigen to elicit an anti-HER-2/neu humoral response in mice

scFv

H-CDR3

L-CDR3

39

CAKKKIGPFDY

NSSNSSPRPNAPVVF

40

CAKNYQIHPFDY

NSSDPDQLLVVF

69

CAKNVHIQPFDY

NSSEPTPPRVVF

  1. aAmino-acid sequences are given in the one letter code. Random loops of 5 or 6 amino acids introduced at position 95 of VH or VL are in bold characters.