Table 2 Summary of studies not included in the meta-analysis

From: CYFRA 21-1 is a prognostic determinant in non-small-cell lung cancer: results of a meta-analysis in 2063 patients

      

CYFRA 21-1 predictive prognostic significance

Authors

Year

CYFRA 21-1 test

Accrual

Histology

Stage

Univariate

Multivariate

Giovanella

1995

IRMA

148

All NSCLC

All

Significant

NA

Takei

1997

ELISA

87

All NSCLC

IIIB–IV

Significant

NA

Hirashima

1998

ELISA

149

All NSCLC

All

Significant

Independent

Niklinski

1998

IRMA

94

All NSCLC

Operable

Significant

Independenta

Nisman

1998 and 1999

ELISA

116

All NSCLC

All

Significant

Independent

Foa

1999

IRMA

62

All NSCLC

Operable

Significant

Independent

Kashiwabara

2000

ELISA

108

SQC

All

Significant

NA

  1. NSCLC=non-small-cell lung cancer; SQC=squamous cell carcinoma; NA=not available.
  2. Total accrual: 764.
  3. aAdjusted and stratified log-rank test on TNM stage.