Figure 5
Immunohistochemistry detection in rat brain tumour in 
contralateral, 
peritumoral (at the border between normal and viable tumour tissues) and 
intratumoral (viable tumour tissue near necrosis) regions. Histological staining was performed by HES. All vessels were stained using anti-collagen antibody (COL) and mature vessels were stained using anti-α smooth muscle actin antibody (SMA). Some vessels in the peritumoral region exhibited both COL and SMA staining (indicated by arrows) suggesting reactive vessels to hypoxic hypoxia.
