Table 1 Physiological parameters of tumour-bearing rats (n=9), at each FiO2 levela

From: Assessment of vascular reactivity in rat brain glioma by measuring regional blood volume during graded hypoxic hypoxia

 

Control

Normoxia

0.15

0.12

0.10

Reoxygenation

MABP (mmHg)

115±20

120±15

95±15

90±20

65±20b

125±25

PaO2 (mmHg)

144.6±16.2

111.2±14.0b

56.5±5.8b

41.8±4.1b

35.4±2.8b

154.1±19.0

SaO2 (%)

99.2±1.5

94.4±5.7

74.1±5.6b

55.2±5.4b

43.1±3.9b

98.9±2.4

PaCO2 (mmHg)

36.0±2.6

35.9±4.8

32.6±2.2

31.1±2.5

28.1±3.3b

34.0±2.6

Pha

7.34±0.03

7.35±0.03

7.39±0.02

7.39±0.02

7.37±0.07

7.34±0.07

Hb (g/dl)

13.6±0.9

13.3±1.3

13.3±0.2

13.1±0.7

12.5±0.9

12.9±0.7

  1. aEvolution of mean arterial blood pressure (MABP), arterial blood gases (PaO2 and PaCO2), arterial saturation of haemoglobin in oxygen (SaO2), arterial pH (pHa) and haemoglobin content (Hb) at each episode of FiO2 (mean±s.d.).
  2. bP<0.05 compared to control value (Scheffé F-test).
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