Table 2 Genetic changes in PG and NPG carcinomas

From: Pathological features and genetic alterations in colorectal carcinomas with characteristics of nonpolypoid growth

 

PG carcinoma (n=86)

NPG carcinoma (n=21)

P-value

APC mutation

 Presence

29 (34%)

5 (24%)

0.3818

 Absence

57 (66%)

16 (76%)

 

Ki-ras mutation

   

 Presence

31 (36%)

0 (0%)

<0.0001

 Absence

55 (64%)

21 (100%)

 

p53 Mutation

   

 Presence

48 (56%)

12 (57%)

0.9124

 Absence

38 (44%)

9 (43%)

 

MSI

   

 Presence

14 (16%)

3 (14%)

0.9806

 Absence

72 (84%)

18 (86%)

 
  1. PG = polypoid growth type; NPG = nonpolypoid growth type; MSI = microsatellite instability.