Table 3 c-erbB-1 mRNA expression and regression (sensitivity and specificity of response prediction for maximum cutoff)

From: Quantitative c-erbB-2 but not c-erbB-1 mRNA expression is a promising marker to predict minor histopathologic response to neoadjuvant radiochemotherapy in oesophageal cancer

 

Regression grading

 

c-erbB-1a

Grades I/II (MiHRb)

Grades III/IV (MaHRc)

Total: n (%)

⩽3.318: n (%)

19 (52.8%)

12 (33.3%)

31 (86.1%)

>3.318: n (%)

5 (13.9%)

∅

5 (13.9%)

Total: n (%)

24 (66.7%)

12 (33.3%)

36 (100%)

  1. aDichotomised c-erbB-1 mRNA levels.
  2. bMinor histopathologic response.
  3. cMajor histopathologic response.
  4. Prediction of MiHR (c-erbB1>3.32): sensitivity 20.8%, specificity: 100% χ2-analysis (Fisher's exact test): P=0.15.
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