Table 4 c-erbB-2 mRNA expression and regression (sensitivity and specificity of response prediction)

From: Quantitative c-erbB-2 but not c-erbB-1 mRNA expression is a promising marker to predict minor histopathologic response to neoadjuvant radiochemotherapy in oesophageal cancer

 

Regression grading

 

c-erbB-2a

Grades I/II (MiHRb)

Grades III/IV (MaHRc)

Total: n (%)

⩽1 or ⩽1.06: n (%)d

14 (38.9%)

12 (33.3%)

26 (72.2%)

>1 or >1.06: n (%)d

10 (27.8%)

∅

10 (27.8%)

Total: n (%)

24 (66.7%%)

12 (33.3%)

36 (100%)

  1. aDichotomised c-erbB-2 mRNA levels.
  2. bMinor histopathologic response.
  3. cMajor histopathologic response.
  4. dAll values remain identical if maximum cutoff at 1.06 was chosen from ROC curves. χ2-analysis (Fisher's exact test): P=0.015.
  5. Prediction of MiHR (c-erbB2 >1): sensitivity 41.6%, specificity: 100%.
Back to article page