Figure 2

Representative autoradiographs of microsatellite analyses for LOH using multiple 3p markers in the microdissected primary lung adenocarcinoma and normal epithelium from a cancer patient (No. 477). The markers are indicated on the left of the autoradiograph panel. Black arrowheads indicate main allele bands and white arrowheads indicate microsatellite instability bands. Asterisks indicate allelic loss. Microsatellite instabilities were seen at D3S1573 and D3S1274. W=well-differentiated portion; M=moderately differentiated portion; P=poorly differentiated portion; N=histologically normal epithelium.