Figure 3

Left: diagram of the short arm of chromosome 3 (3p) showing the nine microsatellite markers used in the allelotyping analysis. Their order and approximate locations are derived from the Genome Database. Right: summary of all 3p allelotyping results with nine microsatellite markers in lung adenocarcinoma. Solid circles, LOH; open circles, retention of heterozygosity; grey circle, noninformative; hatched circles, homozygous deletion. For each individual tumour analysed, the case number and corresponding grade of differentiation are indicated above the lanes. W=well-differentiated portion; M=moderately differentiated portion; P=poorly differentiated portion.