Table 1 Loss of heterozygosity at 9 chromosome 3p polymorphic markers in 56 variously differentiated portions of lung adenocarcinomas

From: Allelic losses on chromosome 3p are accumulated in relation to morphological changes of lung adenocarcinoma

  

LOH(%)

Marker

Region

Total

Wa

Ma

Pa

D3S1597

3p25

18/28(64.2)

4/9(44.4)

8/10(80.0)

6/9(66.7)

D3S2432

3p22–24

22/47(46.8)

7/15(46.7)

6/15(40.0)

9/17(52.9)

D3S1612

3p22–24

6/8(75.0)

2/2(100)

1/1(100)

3/5(60.0)

D3S1478

3p21.3

24/41(58.5)

5/13(38.4)

10/14(71.4)

9/14(64.2)

D3S4597

3p21.3

10/14(71.4)

4/6(66.6)

2/3(66.6)

4/5(80.0)

D3S4622

3p21.3

16/21(76.2)

4/5(80.0)

5/7(71.4)

7/9(77.8)

D3S1573

3p21.2–21.3

21/34(61.8)

5/10(50.0)

8/12(66.7)

8/12(66.7)

D3S1234

3p14.2

15/35(42.9)

6/11(54.5)

4/11(36.4)

5/13(38.5)

D3S1274

3p12

16/35(45.7)

3/9(33.3)

7/13(53.8)

6/13(46.2)

 

Any region

46/56(82.1)

15/17(88.2)

15/19(78.9)

16/20(80.0)

  1. aW=well-differentiated portion; M=moderately differentiated portion; P=poorly differentiated portion.