Table 3 Results of Cox's proportional-hazard regression analysis (univariate) of metastatic rate on A-1012G, Fok 1 and Taq 1 genotypes, and on A-1012G genotype combinations with Fok 1 and Taq 1

From: A novel polymorphism in the 1A promoter region of the vitamin D receptor is associated with altered susceptibilty and prognosis in malignant melanoma

Polymorphisms

Genotype

Number

HR

95% CI

Significance

A-1012G

GG/AG

110

1

  
 

AA

59

2.9

1.1–7.5

P=0.03

Fok

FF/Ff

140

1

  
 

Ff

30

1.3

0.4–4.1

P=0.6

Taq

TT/Tt

143

1

  
 

Tt

26

1.5

0.5–4.6

P=0.5

Fok/Taq

Other genotypes

165

1

  
 

ff/tt

4

2.2

0.3–16.3

P=0.5

A-1012G/Taq

Other genotypes

130

1

  
 

AATT

27

2.5

0.9–7.4

P=0.1

 

Aatt

11

3.1

0.8–11.2

P=0.1

A-1012G/Fok

Other genotypes

130

1

  
 

AAFF

30

4.3

1.5–12.4

P=0.006

 

AAff

9

8.6

2.5–29.6

P=0.001

 

AAFF/Ff

50

1

  
 

AAff

9

4.7

1.2–18.6

P=0.03

  1. HR=hazard ratio; CI=95% confidence interval for hazard ratio estimate. Bold numerals represent statistically significant results.
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