Table 2 Association between ATM SNPs and prostate cancer
From: ATM polymorphisms as risk factors for prostate cancer development
Rare allele frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
SNP | Controls | Cases | Cases (%) | Controls (%) | OR | 95% CI or FCI | P-value | |
5557G>A | 0.166 | 0.151 | GG | 457 (72.7) | 309 (69.4) | 1 | 0.87–1.16 | |
GA | 153 (24.4) | 124 (27.9) | 0.83 | 0.66–1.06 | ||||
AA | 18 (2.9) | 12 (2.7) | 1.01 | 0.49–2.11 | 0.43 | |||
5558A>T | 0.005 | 0.004 | AA | 623 (99.2) | 440 (99) | 1 | ||
AT | 5 (0.8) | 4 (1) | 0.88 | 0.24–3.31 | 0.85 | |||
ivs38-8t>c | 0.036 | 0.036 | TT | 585 (93.2) | 414 (93.0) | 1 | ||
TC | 41 (6.5) | 30 (6.7) | ||||||
CC | 2 (0.3) | 1 (0.3) | ||||||
C carriers | 43 (6.8) | 31 (7.0) | 0.98 | 0.60–1.58 | 0.96 | |||
ivs38-15g>c | 0.004 | 0.008 | GG | 618 (98.4) | 441 (99.1) | 1 | ||
GC | 10 (1.6) | 4 (0.9) | 1.78 | 0.55–5.72 | 0.32 | |||
3161C>G | 0.018 | 0.038 | CC | 578 (92.6) | 402 (96.4) | 1 | ||
CG | 45 (7.2) | 15 (3.6) | ||||||
GG | 1 (0.2) | 0 (0) | ||||||
G carriers | 46 (7.4) | 15 (3.6) | 2.13 | 1.17–3.87 | 0.016 | |||
