Figure 5
From: Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma

Immunohistochemical detection of WWOX protein in normal liver and HCC. Representative immunostaining results of WWOX protein expression. (A) Normal liver tissue sample. Note the strong WWOX cytoplasmic staining of hepatocytes contrasting with the negative staining of the stromal components (lower left corner). (B) HCC tissue sample demonstrating very weak WWOX staining. (C) HCC sample negative for WWOX staining.