Table 3 Psychological distress (GHQ and CWS): mean and median scores and changes over time

From: A randomised comparison of UK genetic risk counselling services for familial cancer: psychosocial outcomes

 

Centre A

Centre B

Centre C

Centre D

Centre E

All centers

Assessment point

(n=31)

(n=29)

(n=33)

(n=34)

(n=35)

(n=162)

Perceived personal risk a

Risk perception: Underestimators/all at elevated risk: n (%)

 Pre-counsel

4/23 (17)

13/31 (42)

11/31 (35)

9/31 (29)

12/28 (43)

49/144 (34)

 1 month

4/23 (17)

9/31 (29)

9/31 (29)

10/31 (32)

5/28 (18)

37/113 (33)

 12 months

5/23 (22)

7/31 (23)

9/31 (29)

9/31 (29)

6/22 (27)

36/109 (33)

GHQ

Mean, Median

Mean, Median

Mean, Median

Mean, Median

Mean, Median

Mean, Median

 Pre-counsel

4.8, 3.0

3.0, 0

3.5, 2.0

2.8, 1.0

3.3,1.0

3.4, 1.5

 1 month

3.4, 0

2.3, 0

3.5, 1.0

2.6, 0

3.0, 0

3.0, 0

 12 months

3.5, 1.0

2.9, 3.0

4.8, 4.0

3.3, 1.0

2.6, 2.0

3.4, 1.0

 12-month pre-counselb (P value)c

−1.29, 0 (P=0.203)

−0.3, 0 (P=0.983)

1.3, 0 (P=0.200)

0.5, 0 (P=0.492)

−0.7, 0 (P=0.639)

−0.2, 0 (P=0.995)

CWS

(n =35)

(n =32)

(n =39)

(n =38)

(n =38)

(n =182)

 Pre-counsel

11.1, 10

12.0, 12

11.0, 10

12.6, 11

11.2,11

11.6, 11

 1 month

11.2, 10

11.1, 11

10.6, 10

11.1, 10

10.6, 10

10.9, 10

 12 month

10.8, 10

11.0, 10

10.5, 10

11.4, 11

10.2, 10

10.8, 10

 12-month pre-counselb (P-value)

−0.3, 0 (P=0.375)

−1.0, −1 (P=0.191)

−0.5, 0 (P=0.107)

−1.3, −1.5 (P=0.005)

−1.0, −1 (P=0.012)

−0.8, −1 (P<0.001)

  1. aThe ‘mean change’ and ‘median change’ for GHQ summary scores and ‘mean change’ and ‘median change’ for CWS summary scores are shown.
  2. bSample excludes subjects deemed by the genetics clinician to be at population risk.
  3. cWilcoxon signed rank test: Shown are ‘mean change’ and ‘median change’ for GHQ summary scores and ‘mean change’ and ‘median change’ for CWS summary scores.
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