Figure 1
From: Recombinant humanised anti-HER2/neu antibody (Herceptin®) induces cellular death of glioblastomas
Apoptosis induction: The A172 cell line expressing HER2/neu undergo apoptosis, following incubation with Herceptin®. Cells were incubated for 24 h with medium (A) or with 25 μg of Herceptin® (B). The cells staining with FITC-conjugated Annexin V and PI. Apoptotic cells were identified as Annexin V positive and PI negative. (C) Time course analysis of PS exposure after incubation of A172 cell line Herceptin® 25 μg ml−1. Only 24 h results are statistically significant (P<0.01).
