Table 1 A list of annotated genes mapped between D1S468 and D1S1608 on chromosome 1p36.3

From: Identification of two contiguous minimally deleted regions on chromosome 1p36.31–p36.32 in oligodendroglial tumours

Locus

Genea

Accession no.

Domainb

Biological function

D1S468

    
 

TP73

NM_005427

p53

Transactivates p53 target genes, suppresses cell proliferation and induces apoptosis

   

Sterile alpha motif

N-terminally truncated isoforms have anti-apoptotic functions

 

KIAA0495

AB007964

Unknown

Hypothetical protein with unknown function

 

FLJ32825

NM_152492

Chromosome segregation ATPase

Hypothetical protein with unknown function

 

KIAA1185

NM_020710

Leucine-rich repeat

Hypothetical protein with unknown function

   

Phenylalanyl-tRNA synthetase

 
 

KJAA0562

NM_014704

Unknown

Hypothetical protein with unknown function

 

DFFB

NM_004402

CIDE-N domain

Involved in both DNA fragmentation and chromatin condensation during apoptosis

 

LOC339448

XM_290902

Unknown

Hypothetical protein with unknown function

D1S2845

    

D1S2893

    

D1S2660

    
 

SHREW1

NM_018836

Transmembrane

Binds to E-cadherin and β-catenin in adherens junctions in polarised epithelial cells

D1S1608

    
  1. aBased on reference human genome sequence Build 34.
  2. bBased on LocusLink (http://www.ncbi.nlm.nih.gov/LocusLink) and InterProScan (http://www.ebi.ac.uk/interpro).
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