Table 2 Acute toxicities (worst grade)
Toxicities | Grade | 850 mg m−2 day−1 | 1000 mg m−2 day−1 | 1250 mg m−2 day−1 | 1650 mg m−2 day−1 | 1800 mg m−2 day−1 | 2000 mg m−2 day−1 |
|---|---|---|---|---|---|---|---|
Haemoglobin | |||||||
0 | 1 | 4 | 2 | 2 | 5 | 4 | |
1 | 0 | 0 | 0 | 1 | 2 | 1 | |
2 | 2 | 2 | 1 | 0 | 1 | 0 | |
Neutrophils | |||||||
0 | 3 | 6 | 3 | 3 | 7 | 5 | |
1 | 0 | 0 | 0 | 0 | 1 | 0 | |
Platelets | |||||||
0 | 3 | 5 | 2 | 2 | 6 | 5 | |
1 | 0 | 1 | 1 | 1 | 2 | 0 | |
Genitourinary | |||||||
0 | 1 | 2 | 3 | 1 | 2 | 2 | |
1 | 2 | 2 | 0 | 1 | 6 | 2 | |
2 | 0 | 1 | 0 | 1 | 0 | 1 | |
3 | 0 | 1 | 0 | 0 | 0 | 0 | |
Lower GI | |||||||
0 | 0 | 2 | 0 | 1 | 2 | 0 | |
1 | 2 | 1 | 3 | 2 | 5 | 1 | |
2 | 1 | 3 | 0 | 0 | 1 | 3 | |
3 | 0 | 0 | 0 | 0 | 0 | 1 | |
Skin | |||||||
0 | 0 | 0 | 0 | 2 | 1 | 1 | |
1 | 1 | 1 | 3 | 1 | 6 | 2 | |
2 | 2 | 5 | 0 | 0 | 1 | 1 | |
3 | 0 | 0 | 0 | 0 | 0 | 1 | |
Hand-foot syndrome | |||||||
0 | 3 | 5 | 3 | 3 | 6 | 5 | |
1 | 0 | 0 | 0 | 0 | 1 | 0 | |
2 | 0 | 1 | 0 | 0 | 1 | 0 | |
