Table 2 Uveal melanoma – primary tumours

From: Loss of nonclassical MHC molecules MIC-A/B expression during progression of uveal melanoma

  

MIC-A/Bb

NKG 2-Dc

CD 57c

No.

TILa

Frequency

Intensity

Frequency

Intensity

Frequency

Intensity

401/99

Ø

 

 

 

331/99

(+)

+d

+

+

(+)

(+)

+

133/99

(+)

(+)

(+)

(+)

+

(+)

+

15/99

+

 

 

 

346/98

Ø

 

 

 

401/97

(+)

 

 

 

290/97

(+)

++

+

++

+

++

+

269/97

(+)

+

+

+

+

+

+

120/92

+

+

+

+

(+)

+

+

  1. aThe inflammatory infiltrate is classified according to the criteria of Elder and Clark as ++: brisk; +: nonbrisk; (+): dim; Ø: absent.
  2. bExpression on melanoma cells.
  3. cExpression on tumour infiltrating lymphocytes.
  4. d−: none, (+): single, +: <40%, ++: <80% positive cells.