Figure 1 | British Journal of Cancer

Figure 1

From: Latent effects of fibronectin, α5β1 integrin, αVβ5 integrin and the cytoskeleton regulate pancreatic carcinoma cell IL-8 secretion

Figure 1

Effect of fibronectin and type I collagen on Mia PaCa2 cell IL-8 secretion, number and spreading. Culture of Mia PaCa2 cells on fibronectin for 72 h produced a dose-dependent increase in IL-8 and cell number (A). However, when expressed as IL-8 per cell, this was not significant (B). Values are expressed as a percentage of those obtained for culture on BSA. When cultured on fibronectin cells took on a fusiform, spread appearance (C) in comparison with the rounded appearance seen when cultured on BSA (D). *P<0.05 vs untreated control.

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