Table 2 Predicted BRCA1 and BRCA2 carrier probabilities for breast and ovarian cancer cases unselected for family history
From: The BOADICEA model of genetic susceptibility to breast and ovarian cancer
| Â | Breast cancer | Ovarian cancer | ||
|---|---|---|---|---|
Age at onset (years) | BRCA1 | BRCA2 | BRCA1 | BRCA2 |
30 | 0.051 (0.055) | 0.050 (0.008) | 0.006 (0.001) | 0.008 (0.000) |
40 | 0.016 (0.029) | 0.020 (0.005) | 0.082 (0.026) | 0.004 (0.003) |
50 | 0.004 (0.012) | 0.015 (0.004) | 0.018 (0.039) | 0.016 (0.006) |
60 | 0.002 (0.003) | 0.012 (0.003) | 0.013 (0.013) | 0.008 (0.005) |
70 | 0.001 (0.000) | 0.008 (0.001) | 0.001 (0.004) | 0.001 (0.004) |
