Table 3 Predicted BRCA1/2 carrier probabilities for a breast cancer case whose mother developed breast cancer

	Age at onset of breast cancer for mother (years)
Index age at onset (years)	30	40	50	60	70
30
BRCA1	0.400 (0.566)	0.223 (0.415)	0.075 (0.244)	0.045 (0.103)	0.042 (0.049)
BRCA2	0.318 (0.036)	0.221 (0.034)	0.196 (0.037)	0.153 (0.030)	0.102 (0.020)
40
BRCA1	0.212 (0.407)	0.087 (0.270)	0.025 (0.144)	0.014 (0.056)	0.013 (0.025)
BRCA2	0.211 (0.033)	0.107 (0.028)	0.082 (0.027)	0.062 (0.021)	0.041 (0.013)
50
BRCA1	0.056 (0.228)	0.020 (0.137)	0.006 (0.067)	0.003 (0.024)	0.003 (0.011)
BRCA2	0.180 (0.035)	0.080 (0.027)	0.061 (0.024)	0.047 (0.018)	0.032 (0.011)
60
BRCA1	0.023 (0.079)	0.008 (0.043)	0.002 (0.020)	0.001 (0.007)	0.001 (0.003)
BRCA2	0.134 (0.028)	0.058 (0.020)	0.045 (0.017)	0.036 (0.012)	0.025 (0.007)
70
BRCA1	0.019 (0.022)	0.006 (0.011)	0.002 (0.005)	0.001 (0.001)	0.001 (0.000)
BRCA2	0.080 (0.016)	0.034 (0.011)	0.028 (0.009)	0.024 (0.006)	0.017 (0.004)

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