Table 7 Predicted annual breast cancer incidence (%) in a monozygotic twin in the years after the diagnosis in the first twin

From: The BOADICEA model of genetic susceptibility to breast and ovarian cancer

 

Years since first twin's diagnosis (years)

First twin age (years)

<5

5–9

10–14

15+

35

0.25

0.43

0.55

0.68

 

0.17(B)

0.26(B)

0.30(B)

0.34(B)

 

0.34(C)

0.77(C)

0.70(C)

0.85(C)

40

0.40

0.52

0.55

0.70

 

0.22(B)

0.26(B)

0.29(B)

0.33(B)

 

0.46(C)

0.42(C)

0.41(C)

0.56(C)

45

0.49

0.53

0.58

0.70

 

0.24(B)

0.27(B)

0.30(B)

0.33(B)

 

0.38(C)

0.37(C)

0.34(C)

0.57(C)

50

0.52

0.57

0.65

0.71

 

0.26(B)

0.29(B)

0.32(B)

0.33(B)

 

0.31(C)

0.29(C)

0.36(C)

0.52(C)

55

0.55

0.63

0.68

0.71

 

0.28(B)

0.31(B)

0.33(B)

0.33(B)

 

0.26(C)

0.34(C)

0.32(C)

0.57(C)

  1. B=BRCAPRO predictions; C=Claus et al predictions.