Figure 2 | British Journal of Cancer

Figure 2

From: Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor α

Figure 2

Detection of proTGFα in the nuclear fraction of human HepG2-hepatoma cells and of rat liver. Nuclear matrix proteins of hepatoma cells (A) and of an untreated male rat liver (B) were subjected to two-dimensional immunoblotting. The gels covered a range of pI 3–8 and Mr 4–40 kDa. (A) Spots 1–4 were analysed by maldi-tof: spot 1 was identified as wild-type proTGFα; * indicates the amino-acid sequence identified, which covers 19% of the total pro-peptide of TGFα.

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