Table 1 Characteristics of patients

From: Multicentre phase II study of bifractionated CPT-11 with bimonthly leucovorin and 5-fluorouracil in patients with metastatic colorectal cancer pretreated with FOLFOX

Characteristics

No.

%

No of patients

35

100

Age (years)

 Median

55

 

 Range

31–79

 

Sex

 Males

26

74

 Females

9

26

Performance status (ECOG)

 0–1

29

83

 2

6

17

Site of primary disease

 Colon

26

74

 Rectum

9

26

Stage at diagnosis

 IIB

3

8

 IIIB

2

6

 IIIC

7

20

 IV

23

66

Prior therapy

 Surgery

30

86

 Radiotherapy

9

26

 Adjuvant chemotherapy

10

28

No of previous chemotherapy

 First line

16

46

 Second line

16

46

Third line

3

8

Metastatic sites

 Liver

25

71

 Lung

10

29

 Nodes

14

40

 Bones

3

9

 Pelvic local recurrence

6

17

 Peritoneum

8

23

 Rising serum markers

1

3

No of metastatic sites

 1

18

51

 2

13

37

3

4

11

  1. ECOG=Eastern Cooperative Oncology Group.