Table 1 Dose escalation and dose limiting toxicity (DLT)

From: Phase I/II study of DHA–paclitaxel in combination with carboplatin in patients with advanced malignant solid tumours

Dose level

N

DHA-paclitaxel (mg m−2)

Carboplatin AUC

Number of patients with DLT

1

3

660

5

0 of 3

2

12

880

5

6 of 12