Figure 1
From: Overexpression of SPARC gene in human gastric carcinoma and its clinic–pathologic significance
Overexpression of SPARC in gastric carcinoma. (A) Northern blot analysis revealed a 2.2-kb SPARC transcript in cancer tissues examined from our surgical specimens. SPARC is overexpressed in all tumour tissues (T) compared to the matched noncancerous adjacent mucosa (N). G10, G20 and G24 are intestinal tumour samples, while G25, G27 and G40 are diffuse-type of tumours. (B) The intensities of SPARC expression on the blots shown in (A) were quantified, and the extent of activation of SPARC expression was determined at each time point. Fold activation indicates the ratio of SPARC signal in tumour to that in normal adjacent tissue. Data are means±s.e. of values from three independent experiments.
