Table 1 Correlation between patient's demographic characteristics and the expression level of SPARC measured by Q-RT–PCR
From: Overexpression of SPARC gene in human gastric carcinoma and its clinic–pathologic significance
Parameters | No. | SPARC (mean±s.e.) | P-value |
|---|---|---|---|
Age (years) | |||
<64 | 22 | 3.72±1.10 | 0.653 |
⩾65 | 21 | 4.86±1.21 | |
Gender | |||
Male | 24 | 3.77±0.94 | 0.874 |
Female | 19 | 4.93±1.34 | |
Location | |||
Proximal | 9 | 5.32±1.82 | 0.228 |
Middle | 13 | 2.30±0.66 | |
Distal | 20 | 5.31±1.36 | |
Size (cm) | |||
⩽2.5 | 12 | 2.20±0.71 | 0.165 |
>2.5 | 31 | 5.08±1.02 | |
Gross type | |||
Borrmann 0–2 | 12 | 2.32±0.81 | 0.108 |
Borrmann 3–4 | 31 | 5.04±1.02 | |
Histology | |||
Intestinal | 16 | 3.89±0.90 | 0.624 |
Diffuse | 27 | 4.51±1.14 | |
Depth of wall invasion | |||
Early (T1) | 10 | 1.81±0.69 | 0.048 |
Advanced (T2–4) | 33 | 5.56±0.97 | |
Lymph node metastasis | |||
Negative | 11 | 0.80±0.16 | <0.001 |
Positive | 32 | 5.48±0.97 | |
Distant metastasis | |||
M0 | 30 | 3.89±0.80 | 0.488 |
M1 | 13 | 5.19±1.87 | |
Pathologic stage | |||
Stage 1 | 11 | 1.67±0.63 | 0.017 |
Stage 2–4 | 32 | 5.18±0.99 | |
Vascular invasion | |||
Negative | 37 | 4.07±0.77 | 0.824 |
Positive | 6 | 5.59±3.26 | |
Lymphatic invasion | |||
Negative | 15 | 1.65±0.50 | 0.004 |
Positive | 28 | 5.69±1.09 | |
Perineural invasion | |||
Negative | 29 | 3.48±0.86 | 0.047 |
Positive | 14 | 5.93±1.58 | |
Peritoneal seeding | |||
Negative | 36 | 4.73±0.91 | 0.508 |
Positive | 7 | 1.99±0.60 |
