Figure 5 | British Journal of Cancer

Figure 5

From: Quantifying trade-offs: quality of life and quality-adjusted survival in a randomised trial of chemotherapy in postmenopausal patients with lymph node-negative breast cancer

Figure 5

Threshold utility analysis of the total sample (N=1669). The diagonal lines indicate the units of months gained in Q-TWiST for different utilities for Tox and Rel. The utility for TWiST is defined as utwist=1 (i.e. reference state). The solid line labelled 0 is the threshold above which CMF followed by Tam results in improved Q-TWiST. The area below 0 with hatch marks represents improved Q-TWiST for Tam alone. The shaded region (top left) represents utilities (ut and ur) for which the improvement in Q-TWiST is statistically significant (P0.05). S=significant and NS=not significant.

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