Table 4 Calculated utility coefficients

From: Quantifying trade-offs: quality of life and quality-adjusted survival in a randomised trial of chemotherapy in postmenopausal patients with lymph node-negative breast cancer

Health state

N a

SHE

TTO=1−(1−SHE)1.6

Tox (CMF)

   

 Overall

276

0.76

0.89

 ER-negative

59

0.75

0.89

 ER-positive

217

0.76

0.90

TWiST

   

 Tam alone

384

0.80

0.91

 CMF

358

0.80

0.91

 ER-negative overall

161

0.80

0.91

 ER-positive overall

578

0.80

0.91

Rel

   

 Tam alone

23

0.62

0.86

 CMF

14

0.50

0.66

 Total sample

37

0.54

0.71

 ER-negative overall

12

0.54

0.71

 ER-positive overall

24

0.56

0.73

  1. aSample size reflects those patients who experienced that health state and who responded to the SHE question at least once during that health state. SHE=subjective health estimation; TTO=time trade-off ; ER=oestrogen receptor.