Table 1 Patients demographics and main pathological features

From: Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression

Characteristics

No of patients ( n =45)

Age (years)

 <40

12

 >40

33

Sex

 Male

22

 Female

33

VHL disease

 VHL+

8

 VHL−

37

Functional Syndrome

 Present

7

 Absent

38

Size (mm)

 <30

25

 >30

20

Classification according to WHO 2000

 WHO-stage 1=benign endocrine tumours

8

 WHO-stage 2=endocrine tumours of incertain behaviour

11

 WHO-stage 3=well-differentiated endocrine carcinomas

18

 WHO-stage 4=poorly differentiated endocrine carcinomas

8

Necrosis

 N0

33

 N1

12

Ki-67 or mitoses

5

18

 >5

17

Lymph node status

 N0

27

 N1

18

Liver metastasis

 M0

30

 M1

15

Duration of follow-up (months)

 Median

32

 Range

2–86

 Lost to follow-up

2

 Death

11