Figure 1

Diploid and aneuploid DNA histograms of fine-needle aspiration biopsies of the breast. Nuclear DNA content of the cells on the horizontal axis is normalised to the nuclear DNA content of leukocytes (2c denotes diploid DNA content). (A) DNA profile of a fibroadenoma, (B) profile of a genomically stable (gs) aneuploid carcinoma, (C) DNA histogram of a gs diploid carcinoma, and (D) profile of a genomically unstable aneuploid carcinoma.