Figure 2

Centrosome staining of fine-needle aspiration biopsies of genomically stable (gs) breast lesions. Centrosomes are immunostained with a monoclonal antibody against γ-tubulin. The fibroadenoma (A) shows no centrosome aberrations, that is, two centrosomes (red) per nucleus (blue). gs diploid (B, C) and gs aneuploid (D) carcinomas show a low range of supernumerary centrosomes and occasionally centrosomes with larger size (B).