Figure 4

Three significantly different groups of breast lesions regarding the centrosomal status: (1) benign (▪) no centrosomal aberrations; (2) malignant with a low extent of cells with centrosomal aberrations: genomically stable (gs) diploid (○) and gs aneuploid (▴); (3) malignant with a higher extent of cells with centrosomal aberrations: invasive genomically unstable (gu) aneuploid and gu aneuploid in situ (♦). There is a positive linear correlation between SSI (Stemline Scatter Index) and the percentage of cells with centrosome aberrations (r=0.82, P<0.0001).