Table 3 Association of PDGFRA expression with clinicopathological characteristics

From: Genetic alterations and protein expression of KIT and PDGFRA in serous ovarian carcinoma

 

PDGFRA immunohistochemical score

 

Clinicopathological characteristics

Weak

%

Moderate

%

Strong

%

P-value

FIGO stage

 I

12/58

21

83/380

22

9/64

14

0.0483

 II

12/58

21

44/380

12

10/64

16

 

 III

23/58

40

208/380

55

41/64

64

 

 IV

11/58

19

45/380

12

4/64

6

 

Grade

 1

22/59

37

153/375

41

13/63

21

0.0019

 2

11/59

19

103/375

27

15/63

24

 

 3

26/59

44

119/375

32

35/63

56

 

Residual tumour

 ⩽1 cm

24/49

49

178/345

51

20/60

33

0.0330

 >1 cm

25/49

51

167/345

49

40/60

67

 

Age

 <57 years

29/59

49

185/382

48

31/64

48

NS; 0.99

 ⩾57 years

30/59

51

197/382

52

33/64

52

 

Tumour size

 ⩽10 cm

26/58

45

122/377

32

23/61

38

NS; 0.15

 >10 cm

32/58

55

255/377

68

38/61

62

 

Ascites

 No

26/56

46

130/377

34

22/63

35

NS; 0.22

 Yes

30/56

54

247/377

66

41/63

65

 

Ki-67

 0–10%

39/57

68

200/375

53

24/62

39

0.0060

 10–25%

9/57

16

105/375

28

17/62

27

 

 >25%

9/57

16

70/375

19

21/62

34

 

p53

 Normal

27/58

47

155/372

42

17/63

27

NS; 0.053

 Aberrant

31/58

53

217/372

58

46/63

73

 
  1. NS=not significant.