Figure 1 | British Journal of Cancer

Figure 1

From: Pooled peptides from HER-2/neu-overexpressing primary ovarian tumours induce CTL with potent antitumour responses in vitro and in vivo

Figure 1

Cytotoxic responses mediated by MEAMNC bulk CTL after in vitro culture with ACE derived from HLA-A2.1 primary ovarian tumour cells overexpressing HER-2/neu (Ova-1, Ova-2 and Ova-3) or being HER-2/neu− (Ova-4 and Ova-5). Cytotoxicity was tested against various targets also including the autologous primary tumour cells (AuTu) from which the ACE was extracted. In some cases, anti-HLA-A2.1 mAb (αA2) was added throughout the cytotoxicity assay. One experiment of three performed is shown. Mean values±s.d. from triplicate cultures are shown.

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