Figure 1

Genes overexpressed in prostate cancer compared to nonprostate normal tissue. We used microarrays of cDNA clones randomly selected from an LNCaP library to identify genes that were overexpressed in a series of 11 prostate cancer samples compared to a series of 12 nonprostate normal tissues. The top 100 ranked overexpressed clones were identified by DNA sequencing. The figure shows a heat map of the expression patterns of the top 50 ranked clones. The full list of 100 clones is available as Supplementary Table 1 (http://www.icr.ac.uk/array/array.html). The red typeface flags genes that have previously been identified as prostate markers.